--中国科学院遗传与发育生物学研究所

姓　　名：	冯健
职　　称：	研究员
职　　务：
电话/传真：	86-10-64807534
电子邮件：	jfeng@genetics.ac.cn
实验室主页：	http://www.genetics.cas.cn/fengjian
研究方向：	植物-微生物互作促进养分高效吸收利用

简历介绍：

冯健，博士，研究员，博士生导师

学习经历

2001-2005年，南开大学，本科生

2005-2013年，中国科学院遗传与发育生物学研究所，博士研究生

工作经历

2013-2017年，英国John Innes Centre，博士后

2017-2022年，英国剑桥大学Sainsbury Laboratory，博士后

2022年 - 今，中国科学院遗传与发育生物学研究所，研究员

2022年 - 今，中国科学院-英国约翰英纳斯中心植物和微生物科学联合研究中心(CEPAMS)，研究员

期刊任职

2023年 - 今，Journal of Genetics and Genomics青年编委

研究领域：

本研究组主要开展植物-微生物互作促进养分高效吸收利用相关研究，以苜蓿等作物为材料，深入探索植物根系与根际促生菌间的互作调控机制，挖掘控制养分高效和环境韧性的关键因子，为培育环境智能作物提供理论支撑。

社会任职：

获奖及荣誉：

承担科研项目情况：

代表论著：

Peer-reviewed articles

1. Shen, L., Yi, C., Liu, Y., Han, F., and Feng, J. (2025). Two complete telomere-to-telomere Medicago genomes reveal the landscape and evolution of centromeres. Mol Plant. 10.1016/j.molp.2025.07.016.

2. Jhu, M.Y., and Feng, J. (2024). The secret of self-fertilizing plants: NIN-NAD1’s role in symbiotic nitrogen fixation. Plant Cell 36, 4291-4292. 10.1093/plcell/koae237.

3. Shen, L., and Feng, J. (2023). NIN-at the heart of NItrogen-fixing Nodule symbiosis. Front Plant Sci 14, 1284720. 10.3389/fpls.2023.1284720.

4. Jing, H., Yang, X., Emenecker, R.J., Feng, J., Zhang, J., Figueiredo, M.R.A., Chaisupa, P., Wright, R.C., Holehouse, A.S., Strader, L.C., and Zuo, J. (2023). Nitric oxide-mediated S-nitrosylation of IAA17 protein in intrinsically disordered region represses auxin signaling. J Genet Genomics 50, 473-485. 10.1016/j.jgg.2023.05.001.

5. Feng, J., Lee, T., Schiessl, K., and Oldroyd, G.E.D. (2021). Processing of NODULE INCEPTION controls the transition to nitrogen fixation in root nodules. Science 374, 629-632. 10.1126/science.abg2804.

6. Chen, L., Wu, R., Feng, J., Feng, T., Wang, C., Hu, J., Zhan, N., Li, Y., Ma, X., Ren, B., et al. (2020). Transnitrosylation mediated by the non-canonical catalase ROG1 regulates nitric oxide signaling in plants. Dev Cell 53, 444-457 e445. 10.1016/j.devcel.2020.03.020.

7. Feng, J., Chen, L., and Zuo, J. (2019). Protein S-Nitrosylation in plants: Current progresses and challenges. J Integr Plant Biol 61, 1206-1223. 10.1111/jipb.12780.

8. Zhan, N., Wang, C., Chen, L., Yang, H., Feng, J., Gong, X., Ren, B., Wu, R., Mu, J., Li, Y., et al. (2018). S-Nitrosylation targets GSNO reductase for selective autophagy during hypoxia responses in plants. Mol Cell 71, 142-154 e146. 10.1016/j.molcel.2018.05.024.

9. Wang, Q., Nian, J., Xie, X., Yu, H., Zhang, J., Bai, J., Dong, G., Hu, J., Bai, B., Chen, L., et al. (2018). Genetic variations in ARE1 mediate grain yield by modulating nitrogen utilization in rice. Nat Commun 9, 735. 10.1038/s41467-017-02781-w.

10. Zhao, W., Guan, C., Feng, J., Liang, Y., Zhan, N., Zuo, J., and Ren, B. (2016). The Arabidopsis CROWDED NUCLEI genes regulate seed germination by modulating degradation of ABI5 protein. J Integr Plant Biol 58, 669-678. 10.1111/jipb.12448.

11. Yang, X., Nian, J., Xie, Q., Feng, J., Zhang, F., Jing, H., Zhang, J., Dong, G., Liang, Y., Peng, J., et al. (2016). Rice ferredoxin-fependent glutamate synthase regulates nitrogen-carbon metabolomes and is genetically differentiated between japonica and indica subspecies. Mol Plant 9, 1520-1534. 10.1016/j.molp.2016.09.004.

12. Yang, H., Mu, J., Chen, L., Feng, J., Hu, J., Li, L., Zhou, J.M., and Zuo, J. (2015). S-nitrosylation positively regulates ascorbate peroxidase activity during plant stress responses. Plant Physiol 167, 1604-1615. 10.1104/pp.114.255216.

13. Jing, H., Yang, X., Zhang, J., Liu, X., Zheng, H., Dong, G., Nian, J., Feng, J., Xia, B., Qian, Q., et al. (2015). Peptidyl-prolyl isomerization targets rice Aux/IAAs for proteasomal degradation during auxin signalling. Nat Commun 6, 7395. 10.1038/ncomms8395.

14. Guan, C., Wang, X., Feng, J., Hong, S., Liang, Y., Ren, B., and Zuo, J. (2014). Cytokinin antagonizes abscisic acid-mediated inhibition of cotyledon greening by promoting the degradation of ABSCISIC ACID INSENSITIVE5 protein in Arabidopsis. Plant Physiol 164, 1515-1526. 10.1104/pp.113.234740.

15. Ren, B., Chen, Q., Hong, S., Zhao, W., Feng, J., Feng, H., and Zuo, J. (2013). The Arabidopsis eukaryotic translation initiation factor eIF5A-2 regulates root protoxylem development by modulating cytokinin signaling. Plant Cell 25, 3841-3857. 10.1105/tpc.113.116236.

16. Feng, J., Wang, C., Chen, Q., Chen, H., Ren, B., Li, X., and Zuo, J. (2013). S-nitrosylation of phosphotransfer proteins represses cytokinin signaling. Nat Commun 4, 1529. 10.1038/ncomms2541.

17. Feng, H., Chen, Q., Feng, J., Zhang, J., Yang, X., and Zuo, J. (2007). Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death. Plant Physiol 144, 1531-1545. 10.1104/pp.107.098079.

18. 陈立超^* 詹妮^* 李彦莎冯健左建儒. (2019) 植物蛋白质 S-亚硝基化修饰的检测与分析. 植物学报 54: 497-502. (^*同等贡献)

Book chapters

1. Feng, J., Shi, Y., Yang, S., and Zuo, J. Chapter 3-Cytokinins, In Hormone Metabolism and Signaling in Plants, edited by Li, J., Li, C., and Smith, SM, Academic Press, 2017, Pages 77-106, ISBN 9780128115626

2. 任勃^* 王兴春^* 冯健^* 杨淑华左建儒 (2012) 细胞分裂素 (pp. 40-64, 许智宏薛红卫主编《植物激素作用的分子机理》)，上海科学出版社. (^*同等贡献)