姓  名: 陈明生
    职  称: 研究员
    职  务:
    电话/传真: 86-10-64806540
    电子邮件: mschen@genetics.ac.cn
    实验室主页:
    研究方向: 植物比较基因组学研究

    简历介绍:

    陈明生 男,博士,1966年生。研究员,博士生导师。
        1988年南开大学生物系毕业;1991年获中科院遗传所硕士学位;1998年获Purdue University博士学位;1999-2000年在University of California, San Diego从事博士后研究;2001-2002年在Clemson University Genomics Institute任Research Assistant Professor;2002年至今任中科院遗传发育所研究员。2002年获国家杰出青年科学基金的资助;

    研究领域:

    禾本科植物的比较基因组学和基因组进化

    社会任职:

    获奖及荣誉:

    承担科研项目情况:

    代表论著:

    近期发表的代表性论文(*Corresponding author or Co-corresponding author)

    1. Sun, Y., Liu, Y., Shi, J., Wang, L., Liang, C., Yang, J., Chen, J., and Chen, M. (2023). Biased mutations and gene losses underlying diploidization of the tetraploid broomcorn millet genome. Plant J 113, 787-801.
    2. Tian, P., Zhang, X., Xia, R., Liu, Y., Wang, M., Li, B., Liu, T., Shi, J., Wing, R.A., Meyers, B.C., and Chen, M. (2021). Evolution and diversification of reproductive phased small interfering RNAs in Oryza species. New Phytol 229, 2970-2983.
    3. Liao, Y., Zhang, X., Li, B., Liu, T., Chen, J., Bai, Z., Wang, M., Shi, J., Walling, J.G., Wing, R.A., Jiang, J., and Chen, M.* (2018). Comparison of Oryza sativa and Oryza brachyantha Genomes Reveals Selection-Driven Gene Escape from the Centromeric Regions. Plant Cell 30, 1729-1744.
    4. Li, B.*, Kremling, K.A.G., Wu, P., Bukowski, R., Romay, M.C., Xie, E., Buckler, E.S., and Chen, M.* (2018). Coregulation of ribosomal RNA with hundreds of genes contributes to phenotypic variation. Genome Res 28, 1555-1565.
    5. Stein, J.C., Yu, Y., Copetti, D., Zwickl, D.J., Zhang, L., Zhang, C., Chougule, K., Gao, D., Iwata, A., Goicoechea, J.L., Wei, S., Wang, J., Liao, Y., and et al. (2018). Genomes of 13 domesticated and wild rice relatives highlight genetic conservation, turnover and innovation across the genus Oryza. Nat Genet 50, 285-296.
    6. Bai, Z., Chen, J., Liao, Y., Wang, M., Liu, R., Ge, S., Wing, R.A., and Chen, M.* (2016). The impact and origin of copy number variations in the Oryza species. BMC Genomics 17, 261.
    7. Wang, M., Yu, Y., Haberer, G., Marri, P.R., Fan, C., Goicoechea, J.L., Zuccolo, A., Song, X., Kudrna, D., Ammiraju, J.S., Cossu, R.M., Maldonado, C., Chen, J., Lee, S., Sisneros, N., de Baynast, K., Golser, W., Wissotski, M., Kim, W., Sanchez, P., Ndjiondjop, M.N., Sanni, K., Long, M., Carney, J., Panaud, O., Wicker, T., Machado, C.A., Chen, M.*, Mayer, K.F.*, Rounsley, S.*, and Wing, R.A.* (2014). The genome sequence of African rice (Oryza glaberrima) and evidence for independent domestication. Nat Genet. (*Co-corresponding authors)
    8. Sui, Y., Li, B., Shi, J., and Chen, M.* (2014). Genomic, regulatory and epigenetic mechanisms underlying duplicated gene evolution in the natural allotetraploid Oryza minuta. BMC Genomics 15, 11.
    9. Chen, J., Huang, Q., Gao, D., Wang, J., Lang, Y., Liu, T., Li, B., Bai, Z., Luis Goicoechea, J., Liang, C., Chen, C., Zhang, W., Sun, S., Liao, Y., Zhang, X., Yang, L., Song, C., Wang, M., Shi, J., Liu, G., Liu, J., Zhou, H., Zhou, W., Yu, Q., An, N., Chen, Y., Cai, Q., Wang, B., Liu, B., Min, J., Huang, Y., Wu, H., Li, Z., Zhang, Y., Yin, Y., Song, W., Jiang, J., Jackson, S.A., Wing, R.A., and Chen, M.* (2013). Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution. Nature Communications 4, 1595.
    10. Yang, L., Liu, T., Li, B., Sui, Y., Chen, J., Shi, J., Wing, R.A., and Chen, M.* (2012). Comparative sequence analysis of the Ghd7 orthologous regions revealed movement of Ghd7 in the grass genomes. PLoS One 7, e50236.
    11. Gao, D., Chen, J., Chen, M., Meyers, B.C., and Jackson, S. (2012). A highly conserved, small LTR retrotransposon that preferentially targets genes in grass genomes. PLoS One 7, e32010.
    12. Sanyal, A., Jetty, A.S., Lu, F., Yu, Y., Rambo, T., Currie, J., Kollura, K., Kim, H.R., Chen, J., Ma, J., San Miguel, P., Chen, M.*, Wing, R.A.*, and Jackson, S.A.* (2010). Orthologous comparisons of the Hd1 region across genera reveal Hd1 gene lability within diploid Oryza species and disruptions to microsynteny in sorghum. Mol Biol Evol 27, 2487.
    13. Chen, M.*, Lu, F., Jackson, S.A., and Wing, R.A. (2010). Dynamic Genome Evolution of Oryza, - A Genus-Wide Comparative Analysis. In DARWIN’S HERITAGE TODAY: Proceedings of the Darwin 200 Beijing International Conference, M. Long, H. Gu, and Z. Zhou, eds. (Beijing, Higher Education Press), pp. 76-83.
    14. Wang, C., Chen, J., Zhi, H., Yang, L., Li, W., Wang, Y., Li, H., Zhao, B., Chen, M.*, and Diao, X.* (2010). Population genetics of foxtail millet and its wild ancestor. BMC Genet 11, 90.
    15. Lu, F., Ammiraju, J. S., Sanyal, A., Zhang, S., Song, R., Chen, J., Li, G., Sui, Y., Song, X., Cheng, Z., de Oliveira, A. C., Bennetzen, J. L.*, Jackson, S.*, Wing, R. A.*, and Chen, M*. (2009). Comparative sequence analysis of the MONOCULM1 orthologous regions in fourteen Oryza genomes. Proc Natl Acad Sci U S A 106, 2071-2076.
    16. Ammiraju, J. S., Lu, F., Sanyal, A., Yu, Y., Song, X., Jiang, N., Pontaroli, A. C., Rambo, T., Currie, J., Collura, K., Talag, J., Fan, C., Goicoechea, J. L., Zuccolo, A., Chen, J., Bennetzen, J. L., Chen, M.*, Jackson, S.*, and Wing, R. A.* (2008). Dynamic Evolution of Oryza Genomes Is Revealed by Comparative Genomic Analysis of a Genus-Wide Vertical Data Set. Plant Cell 20, 3191-3209.