--中国科学院遗传与发育生物学研究所

姓　　名：	谢旗
职　　称：	研究员
职　　务：
电话/传真：	86-10-64806619(O);86-10-64806620(L)
电子邮件：	qxie@genetics.ac.cn
实验室主页：
研究方向：	泛素介导的蛋白修饰及植物逆境胁迫信号传导的分子机制

简历介绍：

谢旗，博士，研究员，博士生导师

　　1987年中山大学学士。1990年广东省微生物研究所硕士。1994年西班牙Universidad de Madrid大学博士。1995年至1998年分别在Universidad de Madrid 及美国Rockefeller University继续博士后工作。1998年被聘为新加坡国立大学分子农业生物学学院Research Fellow，后任该学院植物细胞研究室执行主任。回国前任新加坡国立大学Temasek Life Sciences Laboratory分子与细胞研究室执行主任(Acting Principal Investigator)。2002年起任中山大学生命科学学院长江学者特聘教授。2003年国家杰出青年科学基金获得者。2008年获经国务院批准享受政府特殊津贴专家。现担任国家重大科学研究计划--植物蛋白修饰和降解研究项目的首席科学家。
　　

研究领域：

主要研究内容：
　　1. 泛素蛋白酶体途径介导的蛋白修饰机制
　　泛素蛋白修饰（Ubiquitination）是真核生物特有的蛋白翻译后修饰，它直接地调节生命活动中有关时空特异变化的生物学功能。虽然已在泛素蛋白酶体系统调控植物正常生长发育以及植物对环境响应研究方面取得了一些进展，但对其详细的信号传导机理尚待进一步探讨。尤其是在植物与环境的相互作用领域，关于蛋白泛素修饰参与植物抵抗逆境胁迫的作用机制的研究还处于起步阶段。基于双子叶植物拟南芥及单子叶植物水稻的基因组学和遗传学较其它植物研究得更为深入，我们利用拟南芥和水稻为模式植物，着重于以下几个方面的研究：（1）从功能基因组学方面研究拟南芥中不同E2家族成员的共性及特异性，并且建立适合各种调控途径的体内外反应检测体系，研究E2与E3的特异性结合及生物学功能。（2）研究拟南芥和水稻中单亚基类泛素蛋白连接酶（E3）的两大重要家族（RING finger及 U-box家族）的功能，采取点面结合的方式，利用基因组学、生物化学及遗传学手段阐明该类蛋白的功能网络、作用对象及机制。（3）试图阐明泛素蛋白降解，特别是ERAD途径对植物生长发育的调控机制以及在植物逆境胁迫中的调控机制。

2. 植物与生物胁迫因子的相互作用及对非生物胁迫因子的响应及信号传导
　　我们分别利用正向和反向遗传学的方法，以模式植物拟南芥（Arabidopsis）为材料来研究植物对盐、干旱、冷等非生物胁迫的响应机制及信号传导途径，同时以模式植物小盐芥（Thellungiella salsuginea）来研究植物耐盐的分子机理。生长在华东地区海滩盐土上的本土植物种类小盐芥，符合作为遗传研究模式系统的各种标准，它的基因组大小接近拟南芥的两倍，但相对于拟南芥最高只能在75mM NaCl的浓度下完成其生活史，小盐芥则能在超过300mM NaCl浓度下完成生活史。因此，用小盐芥作为材料，通过系统的遗传学分析将有可能发现耐盐基因，揭示植物耐盐的分子机制。通过导入耐盐基因来获得抗逆的转基因经济作物，将扩大其种植范围和提高作物产量。

　　以双生病毒(Geminivirus)与植物的相互作用为模式研究植物与生物胁迫因子的相互作用。双生病毒是一组具有双生颗粒形态的单链环状植物DNA病毒。对双生病毒基因组结构、遗传表达机制、复制和转录调控机制及病毒与寄主的相互识别等方面进行深入研究，有助于揭示病毒与寄主植物相互间的作用方式。我们以甜菜曲顶卷叶病毒（Beet Curly Top Virus, BCTV）等双生病毒及模式植物拟南芥为材料, 结合基因组学、酵母双杂交系统及DNA芯片等技术来进行研究，目标是应用一种新的研究植物与病毒相互作用的方法研究植物与生物胁迫因子的相互作用，为防治由双生病毒引起的植物病害提出新的技术方案。

3. 高生物量植物--甜高粱的分子设计
　　甜高粱(Sweet Sorghum，Sorghum saccharatum)是耐旱、耐涝、耐盐碱等抗逆性强的光合效率极高的C4作物。茎秆中汁液含糖量与甘蔗相当。高生物量的甜高粱是高价值畜牧饲料、能源乙醇、造纸纤维和生物合成的基质。结合高通量基因组生物学技术和分子遗传学手段研究甜高粱的耐逆和高生物量分子机制，通过分子设计培育更适合边际土地生长的高生物量及抗逆性强的新品种。

社会任职：

获奖及荣誉：

承担科研项目情况：

代表论著：

主要论著目录.

Zhang, D., Tang, S., Liu, F., Zhao, K., Li, C., Xia, R., Yu, F., Xie, Q., and Xie, P. (2025). Natural variations in Multi‐Grain Spikelet 1 enhance grain number in sorghum. Journal of Integrative Plant Biology. DOI:10.1111/jipb.13871

Shi, J., Mei, C., Ge, F., Hu, Q., Ban, X., Xia, R., Xin, P., Cheng, S., Zhang, G., Nie, J., Zhang, S., Ma, X., Wang, Y., Chu, J., Chen, Y., Wang, B., Wu, W., Li, J., Xie, Q., and Yu, F. (2025). Resistance to Striga parasitism through reduction of strigolactone exudation. Cell. DOI:10.1016/j.cell.2025.01.022

Yu, F., and Xie, Q. (2024). ER-associated ubiquitin-conjugating enzyme: a key regulator of grain yield and stress resistance in crops. Trends Plant Sci 29, 286-289.

Liu, C., Li, Q., Shen, Z., Xia, R., Chen, Q., Li, X., Ding, Y., Yang, S., Serino, G., Xie, Q., and Yu, F. (2024b). The Arabidopsis E3 ubiquitin ligase DOA10A promotes localization of abscisic acid (ABA) receptors to the membrane through mono-ubiquitination in ABA signaling. New Phytol.

Li, W., Liu, W., Xu, Z., Zhu, C., Han, D., Liao, J., Li, K., Tang, X., Xie, Q., Yang, C., and Lai, J. (2024). Heat-induced SUMOylation differentially affects bacterial effectors in plant cells. Plant Cell 36, 2103-2116.

Eckardt, N.A., Avin-Wittenberg, T., Bassham, D.C., Chen, P., Chen, Q., Fang, J., Genschik, P., Ghifari, A.S., Guercio, A.M., Gibbs, D.J., Heese, M., Jarvis, R.P., Michaeli, S., Murcha, M.W., Mursalimov, S., Noir, S., Palayam, M., Peixoto, B., Rodriguez, P.L., Schaller, A., Schnittger, A., Serino, G., Shabek, N., Stintzi, A., Theodoulou, F.L., Ustun, S., van Wijk, K.J., Wei, N., Xie, Q., Yu, F., and Zhang, H. (2024). The lowdown on breakdown: Open questions in plant proteolysis. Plant Cell 36, 2931-2975.

Zhang, X.Y., Tang, L.H., Nie, J.W., Zhang, C.R., Han, X., Li, Q.Y., Qin, L., Wang, M.H., Huang, X., Yu, F., Su, M., Wang, Y., Xu, R.M., Guo, Y., Xie, Q., and Chen, Y.H. (2023a). Structure and activation mechanism of the rice Salt Overly Sensitive 1 (SOS1) Na(+)/H(+) antiporter. Nat Plants.

Zhang, H., Yu, F., Xie, P., Sun, S., Qiao, X., Tang, S., Chen, C., Yang, S., Mei, C., Yang, D., Wu, Y., Xia, R., Li, X., Lu, J., Liu, Y., Xie, X., Ma, D., Xu, X., Liang, Z., Feng, Z., Huang, X., Yu, H., Liu, G., Wang, Y., Li, J., Zhang, Q., Chen, C., Ouyang, Y., and Xie, Q. (2023b). A Ggamma protein regulates alkaline sensitivity in crops. Science 379, eade8416.

Yu, F., Liu, C., Zhang, H., and Xie, Q. (2023). A G protein gamma subunit regulates crop alkaline sensitivity by modulating H2O2 transporter PIP2s. J Mol Cell Biol 15.

Wang, Y., Yue, J., Yang, N., Zheng, C., Zheng, Y., Wu, X., Yang, J., Zhang, H., Liu, L., Ning, Y., Bhadauria, V., Zhao, W., Xie, Q., Peng, Y.L., and Chen, Q. (2023b). An ERAD-related ubiquitin-conjugating enzyme boosts broad-spectrum disease resistance and yield in rice. Nat Food 4, 774-787.

Sun, W.J., Zhang, H.L., Yang, S., Liu, L.J., Xie, P., Li, J., Zhu, Y.Y., Ouyang, Y.D., Xie, Q., Zhang, H.W., and Yu, F.F. (2023b). Genetic modification of Gγ subunit AT1 enhances salt-alkali tolerance in main graminaceous crops. Natl Sci Rev.

Liu, D., Zhang, X., Li, Q., Xiao, Y., Zhang, G., Yin, W., Niu, M., Meng, W., Dong, N., Liu, J., Yang, Y., Xie, Q., Chu, C., and Tong, H. (2023). The U-box ubiquitin ligase TUD1 promotes brassinosteroid-induced GSK2 degradation in rice. Plant Commun 4, 100450.

Ge, F., Xie, P., Wu, Y., and Xie, Q. (2023). Genetic architecture and molecular regulation of sorghum domestication. aBIOTECH 4, 57-71.

Zhang, H., Xie, P., Xu, X., Xie, Q., and Yu, F. (2021). Heterotrimeric G protein signalling in plant biotic and abiotic stress response. Plant Biology 23, 20-30.

Wei, S.W., Xia, R., Chen, C.X., Shang, X.L., Ge, F.Y., Wei, H.M., Chen, H.B., Wu, Y.R., and Xie, Q. (2021). ZmbHLH124 identified in maize recombinant inbred lines contributes to drought tolerance in crops. Plant Biotechnology Journal 19, 2069-2081.

Liu, R.J., Xia, R., Xie, Q., and Wu, Y.R. (2021). Endoplasmic reticulum-related E3 ubiquitin ligases: Key regulators of plant growth and stress responses. Plant Communications 2, 10.

Hao, D.D., Jin, L., Wen, X., Yu, F.F., Xie, Q., and Guo, H.W. (2021). The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis. P Natl Acad Sci USA 118, 10.

Yu, F.F., Cao, X.Q., Liu, G.C., Wang, Q., Xia, R., Zhang, X.Y., and Xie, Q. (2020). ESCRT-I Component VPS23A Is Targeted by E3 Ubiquitin Ligase XBAT35 for Proteasome-Mediated Degradation in Modulating ABA Signaling. Molecular Plant 13, 1556-1569.

Wang, Q., Yu, F.F., and Xie, Q. (2020). Balancing growth and adaptation to stress: Crosstalk between brassinosteroid and abscisic acid signaling. Plant Cell Environ 43, 2325-2335.

Pan, W.B., Lin, B.Y., Yang, X.Y., Liu, L.J., Xia, R., Li, J.G., Wu, Y.R., and Xie, Q. (2020). The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis. P Natl Acad Sci USA 117, 27694-27702.

Lou, L.J., Yu, F.F., Tian, M.M., Liu, G.C., Wu, Y.R., Wu, Y.J., Xia, R., Pardo, J.M., Guo, Y., and Xie, Q. (2020). ESCRT-I Component VPS23A Sustains Salt Tolerance by Strengthening the SOS Module in Arabidopsis. Molecular Plant 13, 1134-1148.

Chen, Z.Q., Zhao, J.H., Chen, Q., Zhang, Z.H., Li, J., Guo, Z.X., Xie, Q., Ding, S.W., and Guo, H.S. (2020a). DNA Geminivirus Infection Induces an Imprinted E3 Ligase Gene to Epigenetically Activate Viral Gene Transcription. Plant Cell 32, 3256-3272.

Chen, Q., Yu, F.F., and Xie, Q. (2020b). Insights into endoplasmic reticulum-associated degradation in plants. New Phytologist 226, 345-350.

Xie, Q., and Xu, Z.H. (2019). Sustainable Agriculture: From Sweet Sorghum Planting and Ensiling to Ruminant Feeding. Molecular Plant 12, 603-606.

Xie, P., Shi, J.Y., Tang, S.Y., Chen, C.X., Khan, A., Zhang, F.X., Xiong, Y., Li, C., He, W., Wang, G.D., Lei, F.M., Wu, Y.R., and Xie, Q. (2019). Control of Bird Feeding Behavior by Tannin1 through Modulating the Biosynthesis of Polyphenols and Fatty Acid-Derived Volatiles in Sorghum. Molecular Plant 12, 1315-1324.

Pan, W.B., Wu, Y.R., and Xie, Q. (2019). Regulation of Ubiquitination Is Central to the Phosphate Starvation Response. Trends in Plant Science 24, 755-769.

Hu, B., Jiang, Z.M., Wang, W., Qiu, Y.H., Zhang, Z.H., Liu, Y.Q., Li, A.F., Gao, X.K., Liu, L.C., Qian, Y.W., Huang, X.H., Yu, F.F., Kang, S., Wang, Y.Q., Xie, J.P., Cao, S.Y., Zhang, L.H., Wang, Y.C., Xie, Q., Kopriva, S., and Chu, C.C. (2019). Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants. Nature Plants 5, 401-413.

Han, J.J., Yang, X.Y., Wang, Q., Tang, L., Yu, F.F., Huang, X.H., Wang, Y.C., Liu, J.X., and Xie, Q. (2019). The beta 5 subunit is essential for intact 26S proteasome assembly to specifically promote plant autotrophic growth under salt stress. New Phytologist 221, 1359-1368.

Li, Y.L., Li, Y.Q., Liu, Y.C., Wu, Y.R., and Xie, Q. (2018). The sHSP22 Heat Shock Protein Requires the ABI1 Protein Phosphatase to Modulate Polar Auxin Transport and Downstream Responses. Plant Physiol 176, 2406-2425.

Zhao, L.N., Li, Y.Q., Xie, Q., and Wu, Y.R. (2017). Loss of CDKC; 2 increases both cell division and drought tolerance in Arabidopsis thaliana. Plant Journal 91, 816-828.

Yu, F.F., and Xie, Q. (2017). Non-26S Proteasome Endomembrane Trafficking Pathways in ABA Signaling. Trends in Plant Science 22, 976-985.

Qi, H., Xia, F.N., Xie, L.J., Yu, L.J., Chen, Q.F., Zhuang, X.H., Wang, Q., Li, F.Q., Jiang, L.W., Xie, Q., and Xiao, S. (2017). TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis. Plant Cell 29, 890-911.

Li, Q.L., Wei, H., Liu, L.J., Yang, X.Y., Zhang, X.S., and Xie, Q. (2017). Unfolded protein response activation compensates endoplasmic reticulum-associated degradation deficiency in Arabidopsis. Journal of Integrative Plant Biology 59, 506-521.

Chen, Q., Liu, R.J., Wang, Q., and Xie, Q. (2017). ERAD Tuning of the HRD1 Complex Component AtOS9 Is Modulated by an ER-Bound E2, UBC32. Molecular Plant 10, 891-894.

Yu, F.F., Wu, Y.R., and Xie, Q. (2016a). Ubiquitin-Proteasome System in ABA Signaling: From Perception to Action. Molecular Plant 9, 21-33.

Yu, F.F., Lou, L.J., Tian, M.M., Li, Q.L., Ding, Y.L., Cao, X.Q., Wu, Y.R., Belda-Palazon, B., Rodriguez, P.L., Yang, S.H., and Xie, Q. (2016b). ESCRT-I Component VPS23A Affects ABA Signaling by Recognizing ABA Receptors for Endosomal Degradation. Molecular Plant 9, 1570-1582.

Shu, K., Liu, X.D., Xie, Q., and He, Z.H. (2016a). Two Faces of One Seed: Hormonal Regulation of Dormancy and Germination. Molecular Plant 9, 34-45.

Shu, K., Chen, Q., Wu, Y.R., Liu, R.J., Zhang, H.W., Wang, S.F., Tang, S.Y., Yang, W.Y., and Xie, Q. (2016b). ABSCISIC ACID-INSENSITIVE 4 negatively regulates flowering through directly promoting Arabidopsis FLOWERING LOCUS C transcription. Journal of Experimental Botany 67, 195-205.

Shu, K., Chen, Q., Wu, Y.R., Liu, R.J., Zhang, H.W., Wang, P.F., Li, Y.L., Wang, S.F., Tang, S.Y., Liu, C.Y., Yang, W.Y., Cao, X.F., Serino, G., and Xie, Q. (2016c). ABI4 mediates antagonistic effects of abscisic acid and gibberellins at transcript and protein levels. Plant Journal 85, 348-361.

Min, H.W., Chen, C.X., Wei, S.W., Shang, X.L., Sun, M.Y., Xia, R., Liu, X.G., Hao, D.Y., Chen, H.B., and Xie, Q. (2016). Identification of Drought Tolerant Mechanisms in Maize Seedlings Based on Transcriptome Analysis of Recombination Inbred Lines. Frontiers in Plant Science 7, 19.

Chen, Q., Zhong, Y.W., Wu, Y.R., Liu, L.J., Wang, P.F., Liu, R.J., Cui, F., Li, Q.L., Yang, X.Y., Fang, S.Y., and Xie, Q. (2016). HRD1-mediated ERAD tuning of ER-bound E2 is conserved between plants and mammals. Nature Plants 2, 7.

Zhang, H.W., Cui, F., Wu, Y.R., Lou, L.J., Liu, L.J., Tian, M.M., Ning, Y., Shu, K., Tang, S.Y., and Xie, Q. (2015). The RING Finger Ubiquitin E3 Ligase SDIR1 Targets SDIR1-INTERACTING PROTEIN1 for Degradation to Modulate the Salt Stress Response and ABA Signaling in Arabidopsis. Plant Cell 27, 214-227.

Yu, F.F., Wu, Y.R., and Xie, Q. (2015). Precise protein post-translational modifications modulate ABI5 activity. Trends in Plant Science 20, 569-575.

Yan, L.H., Wei, S.W., Wu, Y.R., Hu, R.L., Li, H.J., Yang, W.C., and Xie, Q. (2015). High-Efficiency Genome Editing in Arabidopsis Using YAO Promoter-Driven CRISPR/Cas9 System. Molecular Plant 8, 1820-1823.

Wu, Y.R., Li, Y.Q., Liu, Y.C., and Xie, Q. (2015). Cautionary Notes on the Usage of abi1-2 and abi1-3 Mutants of Arabidopsis ABI1 for Functional Studies. Molecular Plant 8, 335-338.

Tian, M.M., Lou, L.J., Liu, L.J., Yu, F.F., Zhao, Q.Z., Zhang, H.W., Wu, Y.R., Tang, S.Y., Xia, R., Zhu, B.G., Serino, G., and Xie, Q. (2015). The RING finger E3 ligase STRF1 is involved in membrane trafficking and modulates salt-stress response in Arabidopsis thaliana. Plant Journal 82, 81-92.

Shu, K., Wu, Y.R., Yang, W.Y., and Xie, Q. (2014). Concurrent Deficiency of Gibberellins and Abscisic Acid Causes Plant Male Sterility. Journal of Genetics and Genomics 41, 601-604.

Zhao, Q.Z., Tian, M.M., Li, Q.L., Cui, F., Liu, L.J., Yin, B.J., and Xie, Q. (2013). A plant-specific in vitro ubiquitination analysis system. Plant Journal 74, 524-533.

Yang, L.P., Fang, Y.Y., An, C.P., Dong, L., Zhang, Z.H., Chen, H., Xie, Q., and Guo, H.S. (2013). C2-mediated decrease in DNA methylation, accumulation of siRNAs, and increase in expression for genes involved in defense pathways in plants infected with beet severe curly top virus. Plant Journal 73, 910-917.

Tian, M.M., and Xie, Q. (2013). Non-26S Proteasome Proteolytic Role of Ubiquitin in Plant Endocytosis and Endosomal Trafficking. Journal of Integrative Plant Biology 55, 54-63.

Shu, K., Zhang, H.W., Wang, S.F., Chen, M.L., Wu, Y.R., Tang, S.Y., Liu, C.Y., Feng, Y.Q., Cao, X.F., and Xie, Q. (2013). ABI4 Regulates Primary Seed Dormancy by Regulating the Biogenesis of Abscisic Acid and Gibberellins in Arabidopsis. Plos Genetics 9, 14.

Serino, G., and Xie, Q. (2013). The Ever Expanding Role of Ubiquitin and SUMO in Plant Biology. Journal of Integrative Plant Biology 55, 5-6.

Kaur, N., Zhao, Q.Z., Xie, Q., and Hu, J.P. (2013). Arabidopsis RING Peroxins are E3 Ubiquitin Ligases that Interact with Two Homologous Ubiquitin Receptor Proteins. Journal of Integrative Plant Biology 55, 108-+.

Zheng, N.Y., Huang, X.H., Yin, B.J., Wang, D., and Xie, Q. (2012). An effective system for detecting protein-protein interaction based on in vivo cleavage by PPV NIa protease. Protein & Cell 3, 921-928.

Zhang, Y.Y., Li, Y., Lai, J.B., Zhang, H.W., Liu, Y.Y., Liang, L.M., and Xie, Q. (2012). Ectopic expression of a LEA protein gene TsLEA1 from Thellungiella salsuginea confers salt-tolerance in yeast and Arabidopsis. Molecular Biology Reports 39, 4627-4633.

Wu, H.J., Zhang, Z.H., Wang, J.Y., Oh, D.H., Dassanayake, M., Liu, B.H., Huang, Q.F., Sun, H.X., Xia, R., Wu, Y.R., Wang, Y.N., Yang, Z., Liu, Y., Zhang, W.K., Zhang, H.W., Chu, J.F., Yan, C.Y., Fang, S., Zhang, J.S., Wang, Y.Q., Zhang, F.X., Wang, G.D., Lee, S.Y., Cheeseman, J.M., Yang, B.C., Li, B., Min, J.M., Yang, L.F., Wang, J., Chu, C.C.,

Chen, S.Y., Bohnert, H.J., Zhu, J.K., Wang, X.J., and Xie, Q. (2012). Insights into salt tolerance from the genome of Thellungiella salsuginea. P Natl Acad Sci USA 109, 12219-12224.

Cui, F., Liu, L.J., Zhao, Q.Z., Zhang, Z.H., Li, Q.L., Lin, B.Y., Wu, Y.R., Tang, S.Y., and Xie, Q. (2012). Arabidopsis Ubiquitin Conjugase UBC32 Is an ERAD Component That Functions in Brassinosteroid-Mediated Salt Stress Tolerance. Plant Cell 24, 233-244.

Cui, F., Liu, L.J., Li, Q.L., Yang, C.W., and Xie, Q. (2012). UBC32 Mediated Oxidative Tolerance in Arabidopsis. Journal of Genetics and Genomics 39, 415-417.

Zhang, Z.H., Chen, H., Huang, X.H., Xia, R., Zhao, Q.Z., Lai, J.B., Teng, K.L., Li, Y., Liang, L.M., Du, Q.S., Zhou, X.P., Guo, H.S., and Xie, Q. (2011). BSCTV C2 Attenuates the Degradation of SAMDC1 to Suppress DNA Methylation-Mediated Gene Silencing in Arabidopsis. Plant Cell 23, 273-288.

Yin, B.J., Gao, T., Zheng, N.Y., Li, Y., Tang, S.Y., Liang, L.M., and Xie, Q. (2011). Generation of glyco-engineered BY2 cell lines with decreased expression of plant-specific glycoepitopes. Protein & Cell 2, 41-47.

Ning, Y.S., Xie, Q., and Wang, G.L. (2011). OsDIS1-mediated stress response pathway in rice. Plant Signaling & Behavior 6, 1684-1686.

Ning, Y.S., Jantasuriyarat, C., Zhao, Q.Z., Zhang, H.W., Chen, S.B., Liu, J.L., Liu, L.J., Tang, S.Y., Park, C.H., Wang, X.J., Liu, X.L., Dai, L.Y., Xie, Q., and Wang, G.L. (2011). The SINA E3 Ligase OsDIS1 Negatively Regulates Drought Response in Rice. Plant Physiol 157, 242-255.

Liu, Y.C., Wu, Y.R., Huang, X.H., Sun, J., and Xie, Q. (2011). AtPUB19, a U-Box E3 Ubiquitin Ligase, Negatively Regulates Abscisic Acid and Drought Responses in Arabidopsis thaliana. Molecular Plant 4, 938-946.

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